How It Works

Recommended by ENTs and Supported by 50 Years of Clinical Research

According to a recent survey of 250 ear, nose and throat physicians (otolaryngologists or ENTs), 77% of recommend OTC products/supplements to their tinnitus patients and of them, 73% recommend the brand Lipo-Flavonoid®.1

Why? Because lemon bioflavonoids and specifically the bioflavonoid eriodyctiol glycoside included in Lipo-Flavonoid have been used to treat tinnitus since the 1960s, when an ENT with a prominent Clinic in Minnesota first described success with their use.2

Today, Lipo-Flavonoid® products combine lemon bioflavonoids with other essential nutrients to help support ear health. Clinical experience reported in medical journals indicates that patients can experience considerable benefit from lemon bioflavonoids.2-8

How? Some have speculated that eriodyctiol glycoside helps block histamine production in the inner ear, a likely cause of inner ear disturbances. Other authors have surmised that the lipotropic agents contained in Lipo-Flavonoid may help to prevent abnormal accumulation of fatty deposits, thereby improving circulation. In 1973, W. Rubin theorized that “[successful] use of eriodyctiol glycoside (bioflavonoids) is possibly based improving vascular permeability.”10 To learn more, click here for a white paper that reviews the history and study of Lipo-Flavonoid for the management of tinnitus.

Sleep Disturbances and Tinnitus: Melatonin May Help

For sleep disturbances, Lipo-Flavonoid now offers a new product containing melatonin - Lipo-Flavonoid® Night.

Each caplet contains the same #1 doctor-recommended1ingredients as original Lipo-Flavonoid Plus with the addition of evening melatonin* to help you fall asleep and stay asleep. For best results, take your morning and midday dose of Lipo-Flavonoid Plus, then take Lipo-Flavonoid Night, with added time-release melatonin, in the evening. Each Lipo-Flavonoid Night caplet contains 3 mg immediate-release melatonin to help fall sleep and 2 mg time-release melatonin to stay asleep.

Melatonin* is a substance produced naturally in the brain and is also available over-the-counter to help regulate sleep and wake cycles. More than 3 million Americans concerned about their sleep patterns are already reaching for melatonin.11

According to a study in Otolaryngology-Head and Neck Surgery,12 patients with tinnitus who took daily melatonin saw improvements in what they’d previously rated as “poor” sleep.

Similarly, in the Annals of Otology, Rhinology & Laryngology,13researchers found “Melatonin is associated with a statistically significant decrease in tinnitus intensity and improved sleep quality in patients with chronic tinnitus.”


To create a relaxing, improved sleep environment, the makers of Lipo-Flavonoid now also offer Sonorest Sleep Tones™ – designed by experts specifically for the ambient noise needs of tinnitus sufferers to help relax and fall asleep.


References:

  1. April 2016 Survey. Clarion Brands Inc. data on file.
  2. Slattery WH, Fayad JN. Medical treatment of Meniere's disease. Otolaryngologic Clinics of North America 1997; 30:1027-37.
  3. Kumar S, Pandey AK. Chemistry and Biological Activities of Flavonoids: An Overview. The Scientific World Journal. 2013;2013:162750. doi:10.1155/2013/162750.
  4. Fetterman BL, Saunders JE, Luxford WM. Prognosis and treatment of sudden sensorineural hearing loss. Am J Otol 1996; 17:529-36.
  5. Arenberg I, Bayer R. Therapeutic Options in Meniere’s Disease. Arch Otolaryngol 1977;103: 589-93.
  6. Shaia F, Sheehy J. Sudden sensori-neural hearing impairment: a report of 1,220 cases. Laryngoscope 1976; 86:389-98.
  7. Herschberg S. Meniere’s disease. J Am Osteopathic Association 1974; 73:540-6.
  8. Wolfson R. Treatment of Meniere’s disease. Modern Treatment (1969) 6,3, 553-567.
  9. Rubin W. Vestibular suppressant drugs. Arch Otolaryngol 1973; 97:135-8
  10. National Health Statistics Reports. Centers for Disease Control and Prevention website http://www.cdc.gov/nchs/data/nhsr/nhsr079.pdf. Accessed November 4, 2016.
  11. Melatonin Pills May Help Ease Tinnitus. WebMD website http://www.webmd.com/sleep-disorders/news/20060224/melatonin-pills-may-help-ease-tinnitus. Accessed October 31, 2016.
  12. Hurtuk A, Dome C, Holloman CH, Wolfe K, Welling DB, Dodson EE, Jacob A. Melatonin: can it stop the ringing?Ann Otol Rhinol Laryngol. 2011 Jul;120(7):433-40. https://www.ncbi.nlm.nih.gov/pubmed/21859051
  13. Williams H, Hedgecock L. Citrus Bioflavonoids, Ascorbic Acid and Other B-vitamins in the Treatment of certain types of neurosensory deafness a preliminary report. Staff meeting of the Mayo Clinic (1962).

* Always consult with a healthcare professional before taking any new dietary supplement. If you are under medical supervision or using any tranquilizers or sedatives, seek the advice of your healthcare professional prior to using melatonin. Consult your healthcare professional prior to using melatonin if you have an autoimmune condition, depressive disorder or are pregnant or lactating. Do not take melatonin when operating machinery or driving a vehicle. People with allergies to soy, wheat, or corn should consult their healthcare professional before taking melatonin. Keep out of reach of children.


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